Conserved Differentially Methylated Elements from One Generation to the Next: Inheritance versus Randomness ================================================================ Authors ------- Astrid Deschenes, Pascal Belleau and Arnaud Droit Description ----------- The methylInheritance package implements a permutation analysis, based on Monte Carlo sampling, for testing the hypothesis that the number of conserved differentially methylated elements, between several generations, is associated to an effect inherited from a treatment and that stochastic effect can be dismissed. The methylInheritance package is an official package of Bioconductor. Installation ------------ We strongly suggest to install the methylInheritance package through Bioconductor: http://bioconductor.org/packages/methylInheritance/ However, it is also possible to install the current github version, through the help of the CRAN devtools package. library(devtools) install_github("adeschen/methylInheritance") In addition, older versions of the package are available on GitHub: https://github.com/adeschen/methylInheritance/releases Description of Package Functionality ------------------------------------ The vignette of the methylInheritance package, which is a document that provides a task-oriented description of the package functionality, is available on Bioconductor website: https://bioconductor.org/packages/release/bioc/vignettes/methylInheritance/inst/doc/methylInheritance.html License ------- This package and the underlying methylInheritance code are distributed under the Artistic license 2.0. You are free to use and redistribute this software. For more information on Artistic 2.0 License see: http://opensource.org/licenses/Artistic-2.0 Bugs/Feature requests --------------------- If you have any bugs or feature requests, [let us know](https://github.com/adeschen/methylInheritance/issues).