les

Identifying Loci of Enhanced Significance in Tiling Microarray Data

Bioconductor version: 2.7

The 'les' package estimates Loci of Enhanced Significance (LES) in tiling microarray data. These are regions of regulation such as found in differential transcription, CHiP-chip or methylation experiments. The package provides a universal framework suitable for identifying regulatory effects in tiling microarray data sets and is independent of the underlying statistics at the level of single probes.

Author: Julian Gehring, Clemens Kreutz, Jens Timmer

Maintainer: Julian Gehring <julian.gehring at fdm.uni-freiburg.de>

To install this package, start R and enter:

    source("http://bioconductor.org/biocLite.R")
    biocLite("les")

To cite this package in a publication, start R and enter:

    citation("les")

Documentation

PDF R Script Introduction to the les package: Identifying Loci of Enhanced Significance in Tiling Array Data
PDF   Reference Manual

Details

biocViews Microarray, Bioinformatics, DifferentialExpression, ChIPchip, DNAMethylation, Transcription
Depends R (>= 2.11.0), methods, graphics, fdrtool
Imports boot, gplots, GSRI(>= 1.1.7), RColorBrewer
Suggests Biobase, limma
System Requirements
License GPL-3
URL http://www.fdmold.uni-freiburg.de/~jgehring/
Depends On Me
Imports Me
Suggests Me
Version 1.0.0
Since Bioconductor 2.7 (R-2.12)

Package Downloads

Package Source les_1.0.0.tar.gz
Windows Binary les_1.0.0.zip (32- & 64-bit)
MacOS 10.5 (Leopard) binary les_1.0.0.tgz
Package Downloads Report Download Stats

Workflows »

Common Bioconductor workflows include:

 

Mailing Lists »

Post questions about Bioconductor packages to our mailing lists. Read the posting guide before posting!

Fred Hutchinson Cancer Research Center