|
multiMiR.Rcheck/tests_i386/testthat.Rout
R Under development (unstable) (2019-03-09 r76216) -- "Unsuffered Consequences"
Copyright (C) 2019 The R Foundation for Statistical Computing
Platform: i386-w64-mingw32/i386 (32-bit)
R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.
R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.
Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.
> library(testthat)
> library(multiMiR)
Welcome to multiMiR.
multiMiR database URL has been set to the
default value: http://multimir.ucdenver.edu/
Database Version: 2.2.0 Updated: 2017-08-08
>
> test_check("multiMiR")
--
-- Table structure for table `mirna`
--
DROP TABLE IF EXISTS `mirna`;
CREATE TABLE `mirna` (
mature_mirna_uid INTEGER UNSIGNED AUTO_INCREMENT, -- mature miRNA unique ID
org VARCHAR(4) NOT NULL, -- organism abbreviation
mature_mirna_acc VARCHAR(20) default NULL, -- mature miRNA accession
mature_mirna_id VARCHAR(20) default NULL, -- mature miRNA ID/name
PRIMARY KEY (mature_mirna_uid),
KEY org (org),
KEY mature_mirna_acc (mature_mirna_acc),
KEY mature_mirna_id (mature_mirna_id)
);
--
-- Table structure for table `target`
--
DROP TABLE IF EXISTS `target`;
CREATE TABLE `target` (
target_uid INTEGER UNSIGNED AUTO_INCREMENT, -- target gene unique ID
org VARCHAR(4) NOT NULL, -- organism abbreviation
target_symbol VARCHAR(80) default NULL, -- target gene symbol
target_entrez VARCHAR(10) default NULL, -- target gene Entrez gene ID
target_ensembl VARCHAR(20) default NULL, -- target gene Ensembl gene ID
PRIMARY KEY (target_uid),
KEY org (org),
KEY target_symbol (target_symbol),
KEY target_entrez (target_entrez),
KEY target_ensembl (target_ensembl)
);
--
-- Table structure for table `mirecords`
--
DROP TABLE IF EXISTS `mirecords`;
CREATE TABLE `mirecords` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
target_site_number INT(10) default NULL, -- target site number
target_site_position INT(10) default NULL, -- target site position
experiment VARCHAR(160) default NULL, -- supporting experiment
support_type VARCHAR(40) default NULL, -- type of supporting experiment
pubmed_id VARCHAR(10) default NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT
);
--
-- Table structure for table `mirtarbase`
--
DROP TABLE IF EXISTS `mirtarbase`;
CREATE TABLE `mirtarbase` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
experiment VARCHAR(160) NOT NULL, -- supporting experiment
support_type VARCHAR(40) NOT NULL, -- type of supporting experiment
pubmed_id VARCHAR(10) default NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT
);
--
-- Table structure for table `tarbase`
--
DROP TABLE IF EXISTS `tarbase`;
CREATE TABLE `tarbase` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
experiment VARCHAR(160) NOT NULL, -- supporting experiment
support_type VARCHAR(40) NOT NULL, -- type of supporting experiment
pubmed_id VARCHAR(10) default NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT
);
--
-- Table structure for table `miranda`
--
DROP TABLE IF EXISTS `miranda`;
CREATE TABLE `miranda` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
conservation REAL NOT NULL, -- conservation score
mirsvr_score REAL NOT NULL, -- mirSVR downregulation score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY conservation (conservation),
KEY mirsvr_score (mirsvr_score)
);
--
-- Table structure for table `targetscan`
--
DROP TABLE IF EXISTS `targetscan`;
CREATE TABLE `targetscan` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
site_type INTEGER UNSIGNED NOT NULL, -- site type (see http://www.targetscan.org/faqs.html)
context_plus_score REAL NOT NULL, -- context+ score
conserved_site ENUM('N','Y'), -- whether the target site is conserved
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY context_plus_score (context_plus_score),
KEY conserved_site (conserved_site)
);
--
-- Table structure for table `diana_microt`
--
DROP TABLE IF EXISTS `diana_microt`;
CREATE TABLE `diana_microt` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
miTG_score REAL NOT NULL, -- miRNA target gene score
UTR3_hit INTEGER UNSIGNED NOT NULL, -- number of 3'-UTR binding sites
CDS_hit INTEGER UNSIGNED NOT NULL, -- number of CDS binding sites
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY miTG_score (miTG_score)
);
--
-- Table structure for table `elmmo`
--
DROP TABLE IF EXISTS `elmmo`;
CREATE TABLE `elmmo` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
p REAL NOT NULL, -- "the posterior probability that the site is under evolutionnary selective pressure"
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY p (p)
);
--
-- Table structure for table `pita`
--
DROP TABLE IF EXISTS `pita`;
CREATE TABLE `pita` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
ddG REAL NOT NULL, -- ddG = dGduplex (microRNA-target hybridization energy) - dGopen (energy required to make the target site accessible)
conservation REAL NOT NULL, -- site conservation (range 0˜1)
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY ddG (ddG),
KEY conservation (conservation)
);
--
-- Table structure for table `microcosm`
--
DROP TABLE IF EXISTS `microcosm`;
CREATE TABLE `microcosm` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
score REAL NOT NULL, -- miRanda score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY score (score)
);
--
-- Table structure for table `pictar`
--
DROP TABLE IF EXISTS `pictar`;
CREATE TABLE `pictar` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
score REAL NOT NULL, -- score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY score (score)
);
--
-- Table structure for table `mirdb`
--
DROP TABLE IF EXISTS `mirdb`;
CREATE TABLE `mirdb` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
score REAL NOT NULL, -- score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY score (score)
);
--
-- Table structure for table `mir2disease`
--
DROP TABLE IF EXISTS `mir2disease`;
CREATE TABLE `mir2disease` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
disease VARCHAR(100) NOT NULL, -- disease
mirna_regulation VARCHAR(20) NOT NULL, -- how miRNA is regulated in the disease (up-regulated, down-regulated or normal)
experiment VARCHAR(40) NOT NULL, -- supporting experiment
year INTEGER UNSIGNED NOT NULL, -- year of the paper
title TEXT NOT NULL, -- title of the paper
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY disease (disease)
);
--
-- Table structure for table `pharmaco_mir`
--
DROP TABLE IF EXISTS `pharmaco_mir`;
CREATE TABLE `pharmaco_mir` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
drug VARCHAR(40) NOT NULL, -- disease
pubmed_id VARCHAR(10) NOT NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY drug (drug)
);
--
-- Table structure for table `phenomir`
--
DROP TABLE IF EXISTS `phenomir`;
CREATE TABLE `phenomir` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
pre_mirna_acc VARCHAR(20) default NULL, -- precursor miRNA accession
pre_mirna_id VARCHAR(20) default NULL, -- precursor miRNA ID
disease VARCHAR(60) NOT NULL, -- disease
disease_class VARCHAR(20) NOT NULL, -- disease class
mirna_expression VARCHAR(30) NOT NULL, -- how miRNA is expressed in the disease
study VARCHAR(40) NOT NULL, -- type of study (in cells, patients, etc)
experiment VARCHAR(40) NOT NULL, -- supporting experiment
pubmed_id VARCHAR(10) NOT NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY disease (disease),
KEY disease_class (disease_class)
);
--
-- Table structure for table `metadata`
--
DROP TABLE IF EXISTS `metadata`;
CREATE TABLE metadata (
name VARCHAR(80) PRIMARY KEY,
value VARCHAR(255)
);
--
-- Table structure for table `map_metadata`
--
DROP TABLE IF EXISTS `map_metadata`;
CREATE TABLE map_metadata (
map_name VARCHAR(80) PRIMARY KEY,
source_name VARCHAR(80) NOT NULL,
source_version VARCHAR(20),
source_date VARCHAR(20),
source_url VARCHAR(255) NOT NULL
);
--
-- Table structure for table `map_counts`
--
DROP TABLE IF EXISTS `map_counts`;
CREATE TABLE map_counts (
map_name VARCHAR(80) PRIMARY KEY,
human_count INTEGER UNSIGNED NOT NULL,
mouse_count INTEGER UNSIGNED NOT NULL,
total_count INTEGER UNSIGNED NOT NULL
);
--
-- Table structure for table `mirna`
--
DROP TABLE IF EXISTS `mirna`;
CREATE TABLE `mirna` (
mature_mirna_uid INTEGER UNSIGNED AUTO_INCREMENT, -- mature miRNA unique ID
org VARCHAR(4) NOT NULL, -- organism abbreviation
mature_mirna_acc VARCHAR(20) default NULL, -- mature miRNA accession
mature_mirna_id VARCHAR(20) default NULL, -- mature miRNA ID/name
PRIMARY KEY (mature_mirna_uid),
KEY org (org),
KEY mature_mirna_acc (mature_mirna_acc),
KEY mature_mirna_id (mature_mirna_id)
);
--
-- Table structure for table `target`
--
DROP TABLE IF EXISTS `target`;
CREATE TABLE `target` (
target_uid INTEGER UNSIGNED AUTO_INCREMENT, -- target gene unique ID
org VARCHAR(4) NOT NULL, -- organism abbreviation
target_symbol VARCHAR(80) default NULL, -- target gene symbol
target_entrez VARCHAR(10) default NULL, -- target gene Entrez gene ID
target_ensembl VARCHAR(20) default NULL, -- target gene Ensembl gene ID
PRIMARY KEY (target_uid),
KEY org (org),
KEY target_symbol (target_symbol),
KEY target_entrez (target_entrez),
KEY target_ensembl (target_ensembl)
);
--
-- Table structure for table `mirecords`
--
DROP TABLE IF EXISTS `mirecords`;
CREATE TABLE `mirecords` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
target_site_number INT(10) default NULL, -- target site number
target_site_position INT(10) default NULL, -- target site position
experiment VARCHAR(160) default NULL, -- supporting experiment
support_type VARCHAR(40) default NULL, -- type of supporting experiment
pubmed_id VARCHAR(10) default NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT
);
--
-- Table structure for table `mirtarbase`
--
DROP TABLE IF EXISTS `mirtarbase`;
CREATE TABLE `mirtarbase` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
experiment VARCHAR(160) NOT NULL, -- supporting experiment
support_type VARCHAR(40) NOT NULL, -- type of supporting experiment
pubmed_id VARCHAR(10) default NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT
);
--
-- Table structure for table `tarbase`
--
DROP TABLE IF EXISTS `tarbase`;
CREATE TABLE `tarbase` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
experiment VARCHAR(160) NOT NULL, -- supporting experiment
support_type VARCHAR(40) NOT NULL, -- type of supporting experiment
pubmed_id VARCHAR(10) default NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT
);
--
-- Table structure for table `miranda`
--
DROP TABLE IF EXISTS `miranda`;
CREATE TABLE `miranda` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
conservation REAL NOT NULL, -- conservation score
mirsvr_score REAL NOT NULL, -- mirSVR downregulation score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY conservation (conservation),
KEY mirsvr_score (mirsvr_score)
);
--
-- Table structure for table `targetscan`
--
DROP TABLE IF EXISTS `targetscan`;
CREATE TABLE `targetscan` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
site_type INTEGER UNSIGNED NOT NULL, -- site type (see http://www.targetscan.org/faqs.html)
context_plus_score REAL NOT NULL, -- context+ score
conserved_site ENUM('N','Y'), -- whether the target site is conserved
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY context_plus_score (context_plus_score),
KEY conserved_site (conserved_site)
);
--
-- Table structure for table `diana_microt`
--
DROP TABLE IF EXISTS `diana_microt`;
CREATE TABLE `diana_microt` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
miTG_score REAL NOT NULL, -- miRNA target gene score
UTR3_hit INTEGER UNSIGNED NOT NULL, -- number of 3'-UTR binding sites
CDS_hit INTEGER UNSIGNED NOT NULL, -- number of CDS binding sites
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY miTG_score (miTG_score)
);
--
-- Table structure for table `elmmo`
--
DROP TABLE IF EXISTS `elmmo`;
CREATE TABLE `elmmo` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
p REAL NOT NULL, -- "the posterior probability that the site is under evolutionnary selective pressure"
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY p (p)
);
--
-- Table structure for table `pita`
--
DROP TABLE IF EXISTS `pita`;
CREATE TABLE `pita` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
ddG REAL NOT NULL, -- ddG = dGduplex (microRNA-target hybridization energy) - dGopen (energy required to make the target site accessible)
conservation REAL NOT NULL, -- site conservation (range 0˜1)
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY ddG (ddG),
KEY conservation (conservation)
);
--
-- Table structure for table `microcosm`
--
DROP TABLE IF EXISTS `microcosm`;
CREATE TABLE `microcosm` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
score REAL NOT NULL, -- miRanda score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY score (score)
);
--
-- Table structure for table `pictar`
--
DROP TABLE IF EXISTS `pictar`;
CREATE TABLE `pictar` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
score REAL NOT NULL, -- score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY score (score)
);
--
-- Table structure for table `mirdb`
--
DROP TABLE IF EXISTS `mirdb`;
CREATE TABLE `mirdb` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
score REAL NOT NULL, -- score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY score (score)
);
--
-- Table structure for table `mir2disease`
--
DROP TABLE IF EXISTS `mir2disease`;
CREATE TABLE `mir2disease` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
disease VARCHAR(100) NOT NULL, -- disease
mirna_regulation VARCHAR(20) NOT NULL, -- how miRNA is regulated in the disease (up-regulated, down-regulated or normal)
experiment VARCHAR(40) NOT NULL, -- supporting experiment
year INTEGER UNSIGNED NOT NULL, -- year of the paper
title TEXT NOT NULL, -- title of the paper
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY disease (disease)
);
--
-- Table structure for table `pharmaco_mir`
--
DROP TABLE IF EXISTS `pharmaco_mir`;
CREATE TABLE `pharmaco_mir` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
drug VARCHAR(40) NOT NULL, -- disease
pubmed_id VARCHAR(10) NOT NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY drug (drug)
);
--
-- Table structure for table `phenomir`
--
DROP TABLE IF EXISTS `phenomir`;
CREATE TABLE `phenomir` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
pre_mirna_acc VARCHAR(20) default NULL, -- precursor miRNA accession
pre_mirna_id VARCHAR(20) default NULL, -- precursor miRNA ID
disease VARCHAR(60) NOT NULL, -- disease
disease_class VARCHAR(20) NOT NULL, -- disease class
mirna_expression VARCHAR(30) NOT NULL, -- how miRNA is expressed in the disease
study VARCHAR(40) NOT NULL, -- type of study (in cells, patients, etc)
experiment VARCHAR(40) NOT NULL, -- supporting experiment
pubmed_id VARCHAR(10) NOT NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY disease (disease),
KEY disease_class (disease_class)
);
--
-- Table structure for table `metadata`
--
DROP TABLE IF EXISTS `metadata`;
CREATE TABLE metadata (
name VARCHAR(80) PRIMARY KEY,
value VARCHAR(255)
);
--
-- Table structure for table `map_metadata`
--
DROP TABLE IF EXISTS `map_metadata`;
CREATE TABLE map_metadata (
map_name VARCHAR(80) PRIMARY KEY,
source_name VARCHAR(80) NOT NULL,
source_version VARCHAR(20),
source_date VARCHAR(20),
source_url VARCHAR(255) NOT NULL
);
--
-- Table structure for table `map_counts`
--
DROP TABLE IF EXISTS `map_counts`;
CREATE TABLE map_counts (
map_name VARCHAR(80) PRIMARY KEY,
human_count INTEGER UNSIGNED NOT NULL,
mouse_count INTEGER UNSIGNED NOT NULL,
total_count INTEGER UNSIGNED NOT NULL
);
== testthat results ===========================================================
OK: 22 SKIPPED: 0 FAILED: 0
>
> proc.time()
user system elapsed
4.50 0.46 6.73
|
multiMiR.Rcheck/tests_x64/testthat.Rout
R Under development (unstable) (2019-03-09 r76216) -- "Unsuffered Consequences"
Copyright (C) 2019 The R Foundation for Statistical Computing
Platform: x86_64-w64-mingw32/x64 (64-bit)
R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.
R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.
Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.
> library(testthat)
> library(multiMiR)
Welcome to multiMiR.
multiMiR database URL has been set to the
default value: http://multimir.ucdenver.edu/
Database Version: 2.2.0 Updated: 2017-08-08
>
> test_check("multiMiR")
--
-- Table structure for table `mirna`
--
DROP TABLE IF EXISTS `mirna`;
CREATE TABLE `mirna` (
mature_mirna_uid INTEGER UNSIGNED AUTO_INCREMENT, -- mature miRNA unique ID
org VARCHAR(4) NOT NULL, -- organism abbreviation
mature_mirna_acc VARCHAR(20) default NULL, -- mature miRNA accession
mature_mirna_id VARCHAR(20) default NULL, -- mature miRNA ID/name
PRIMARY KEY (mature_mirna_uid),
KEY org (org),
KEY mature_mirna_acc (mature_mirna_acc),
KEY mature_mirna_id (mature_mirna_id)
);
--
-- Table structure for table `target`
--
DROP TABLE IF EXISTS `target`;
CREATE TABLE `target` (
target_uid INTEGER UNSIGNED AUTO_INCREMENT, -- target gene unique ID
org VARCHAR(4) NOT NULL, -- organism abbreviation
target_symbol VARCHAR(80) default NULL, -- target gene symbol
target_entrez VARCHAR(10) default NULL, -- target gene Entrez gene ID
target_ensembl VARCHAR(20) default NULL, -- target gene Ensembl gene ID
PRIMARY KEY (target_uid),
KEY org (org),
KEY target_symbol (target_symbol),
KEY target_entrez (target_entrez),
KEY target_ensembl (target_ensembl)
);
--
-- Table structure for table `mirecords`
--
DROP TABLE IF EXISTS `mirecords`;
CREATE TABLE `mirecords` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
target_site_number INT(10) default NULL, -- target site number
target_site_position INT(10) default NULL, -- target site position
experiment VARCHAR(160) default NULL, -- supporting experiment
support_type VARCHAR(40) default NULL, -- type of supporting experiment
pubmed_id VARCHAR(10) default NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT
);
--
-- Table structure for table `mirtarbase`
--
DROP TABLE IF EXISTS `mirtarbase`;
CREATE TABLE `mirtarbase` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
experiment VARCHAR(160) NOT NULL, -- supporting experiment
support_type VARCHAR(40) NOT NULL, -- type of supporting experiment
pubmed_id VARCHAR(10) default NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT
);
--
-- Table structure for table `tarbase`
--
DROP TABLE IF EXISTS `tarbase`;
CREATE TABLE `tarbase` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
experiment VARCHAR(160) NOT NULL, -- supporting experiment
support_type VARCHAR(40) NOT NULL, -- type of supporting experiment
pubmed_id VARCHAR(10) default NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT
);
--
-- Table structure for table `miranda`
--
DROP TABLE IF EXISTS `miranda`;
CREATE TABLE `miranda` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
conservation REAL NOT NULL, -- conservation score
mirsvr_score REAL NOT NULL, -- mirSVR downregulation score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY conservation (conservation),
KEY mirsvr_score (mirsvr_score)
);
--
-- Table structure for table `targetscan`
--
DROP TABLE IF EXISTS `targetscan`;
CREATE TABLE `targetscan` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
site_type INTEGER UNSIGNED NOT NULL, -- site type (see http://www.targetscan.org/faqs.html)
context_plus_score REAL NOT NULL, -- context+ score
conserved_site ENUM('N','Y'), -- whether the target site is conserved
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY context_plus_score (context_plus_score),
KEY conserved_site (conserved_site)
);
--
-- Table structure for table `diana_microt`
--
DROP TABLE IF EXISTS `diana_microt`;
CREATE TABLE `diana_microt` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
miTG_score REAL NOT NULL, -- miRNA target gene score
UTR3_hit INTEGER UNSIGNED NOT NULL, -- number of 3'-UTR binding sites
CDS_hit INTEGER UNSIGNED NOT NULL, -- number of CDS binding sites
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY miTG_score (miTG_score)
);
--
-- Table structure for table `elmmo`
--
DROP TABLE IF EXISTS `elmmo`;
CREATE TABLE `elmmo` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
p REAL NOT NULL, -- "the posterior probability that the site is under evolutionnary selective pressure"
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY p (p)
);
--
-- Table structure for table `pita`
--
DROP TABLE IF EXISTS `pita`;
CREATE TABLE `pita` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
ddG REAL NOT NULL, -- ddG = dGduplex (microRNA-target hybridization energy) - dGopen (energy required to make the target site accessible)
conservation REAL NOT NULL, -- site conservation (range 0˜1)
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY ddG (ddG),
KEY conservation (conservation)
);
--
-- Table structure for table `microcosm`
--
DROP TABLE IF EXISTS `microcosm`;
CREATE TABLE `microcosm` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
score REAL NOT NULL, -- miRanda score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY score (score)
);
--
-- Table structure for table `pictar`
--
DROP TABLE IF EXISTS `pictar`;
CREATE TABLE `pictar` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
score REAL NOT NULL, -- score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY score (score)
);
--
-- Table structure for table `mirdb`
--
DROP TABLE IF EXISTS `mirdb`;
CREATE TABLE `mirdb` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
score REAL NOT NULL, -- score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY score (score)
);
--
-- Table structure for table `mir2disease`
--
DROP TABLE IF EXISTS `mir2disease`;
CREATE TABLE `mir2disease` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
disease VARCHAR(100) NOT NULL, -- disease
mirna_regulation VARCHAR(20) NOT NULL, -- how miRNA is regulated in the disease (up-regulated, down-regulated or normal)
experiment VARCHAR(40) NOT NULL, -- supporting experiment
year INTEGER UNSIGNED NOT NULL, -- year of the paper
title TEXT NOT NULL, -- title of the paper
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY disease (disease)
);
--
-- Table structure for table `pharmaco_mir`
--
DROP TABLE IF EXISTS `pharmaco_mir`;
CREATE TABLE `pharmaco_mir` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
drug VARCHAR(40) NOT NULL, -- disease
pubmed_id VARCHAR(10) NOT NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY drug (drug)
);
--
-- Table structure for table `phenomir`
--
DROP TABLE IF EXISTS `phenomir`;
CREATE TABLE `phenomir` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
pre_mirna_acc VARCHAR(20) default NULL, -- precursor miRNA accession
pre_mirna_id VARCHAR(20) default NULL, -- precursor miRNA ID
disease VARCHAR(60) NOT NULL, -- disease
disease_class VARCHAR(20) NOT NULL, -- disease class
mirna_expression VARCHAR(30) NOT NULL, -- how miRNA is expressed in the disease
study VARCHAR(40) NOT NULL, -- type of study (in cells, patients, etc)
experiment VARCHAR(40) NOT NULL, -- supporting experiment
pubmed_id VARCHAR(10) NOT NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY disease (disease),
KEY disease_class (disease_class)
);
--
-- Table structure for table `metadata`
--
DROP TABLE IF EXISTS `metadata`;
CREATE TABLE metadata (
name VARCHAR(80) PRIMARY KEY,
value VARCHAR(255)
);
--
-- Table structure for table `map_metadata`
--
DROP TABLE IF EXISTS `map_metadata`;
CREATE TABLE map_metadata (
map_name VARCHAR(80) PRIMARY KEY,
source_name VARCHAR(80) NOT NULL,
source_version VARCHAR(20),
source_date VARCHAR(20),
source_url VARCHAR(255) NOT NULL
);
--
-- Table structure for table `map_counts`
--
DROP TABLE IF EXISTS `map_counts`;
CREATE TABLE map_counts (
map_name VARCHAR(80) PRIMARY KEY,
human_count INTEGER UNSIGNED NOT NULL,
mouse_count INTEGER UNSIGNED NOT NULL,
total_count INTEGER UNSIGNED NOT NULL
);
--
-- Table structure for table `mirna`
--
DROP TABLE IF EXISTS `mirna`;
CREATE TABLE `mirna` (
mature_mirna_uid INTEGER UNSIGNED AUTO_INCREMENT, -- mature miRNA unique ID
org VARCHAR(4) NOT NULL, -- organism abbreviation
mature_mirna_acc VARCHAR(20) default NULL, -- mature miRNA accession
mature_mirna_id VARCHAR(20) default NULL, -- mature miRNA ID/name
PRIMARY KEY (mature_mirna_uid),
KEY org (org),
KEY mature_mirna_acc (mature_mirna_acc),
KEY mature_mirna_id (mature_mirna_id)
);
--
-- Table structure for table `target`
--
DROP TABLE IF EXISTS `target`;
CREATE TABLE `target` (
target_uid INTEGER UNSIGNED AUTO_INCREMENT, -- target gene unique ID
org VARCHAR(4) NOT NULL, -- organism abbreviation
target_symbol VARCHAR(80) default NULL, -- target gene symbol
target_entrez VARCHAR(10) default NULL, -- target gene Entrez gene ID
target_ensembl VARCHAR(20) default NULL, -- target gene Ensembl gene ID
PRIMARY KEY (target_uid),
KEY org (org),
KEY target_symbol (target_symbol),
KEY target_entrez (target_entrez),
KEY target_ensembl (target_ensembl)
);
--
-- Table structure for table `mirecords`
--
DROP TABLE IF EXISTS `mirecords`;
CREATE TABLE `mirecords` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
target_site_number INT(10) default NULL, -- target site number
target_site_position INT(10) default NULL, -- target site position
experiment VARCHAR(160) default NULL, -- supporting experiment
support_type VARCHAR(40) default NULL, -- type of supporting experiment
pubmed_id VARCHAR(10) default NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT
);
--
-- Table structure for table `mirtarbase`
--
DROP TABLE IF EXISTS `mirtarbase`;
CREATE TABLE `mirtarbase` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
experiment VARCHAR(160) NOT NULL, -- supporting experiment
support_type VARCHAR(40) NOT NULL, -- type of supporting experiment
pubmed_id VARCHAR(10) default NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT
);
--
-- Table structure for table `tarbase`
--
DROP TABLE IF EXISTS `tarbase`;
CREATE TABLE `tarbase` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
experiment VARCHAR(160) NOT NULL, -- supporting experiment
support_type VARCHAR(40) NOT NULL, -- type of supporting experiment
pubmed_id VARCHAR(10) default NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT
);
--
-- Table structure for table `miranda`
--
DROP TABLE IF EXISTS `miranda`;
CREATE TABLE `miranda` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
conservation REAL NOT NULL, -- conservation score
mirsvr_score REAL NOT NULL, -- mirSVR downregulation score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY conservation (conservation),
KEY mirsvr_score (mirsvr_score)
);
--
-- Table structure for table `targetscan`
--
DROP TABLE IF EXISTS `targetscan`;
CREATE TABLE `targetscan` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
site_type INTEGER UNSIGNED NOT NULL, -- site type (see http://www.targetscan.org/faqs.html)
context_plus_score REAL NOT NULL, -- context+ score
conserved_site ENUM('N','Y'), -- whether the target site is conserved
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY context_plus_score (context_plus_score),
KEY conserved_site (conserved_site)
);
--
-- Table structure for table `diana_microt`
--
DROP TABLE IF EXISTS `diana_microt`;
CREATE TABLE `diana_microt` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
miTG_score REAL NOT NULL, -- miRNA target gene score
UTR3_hit INTEGER UNSIGNED NOT NULL, -- number of 3'-UTR binding sites
CDS_hit INTEGER UNSIGNED NOT NULL, -- number of CDS binding sites
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY miTG_score (miTG_score)
);
--
-- Table structure for table `elmmo`
--
DROP TABLE IF EXISTS `elmmo`;
CREATE TABLE `elmmo` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
p REAL NOT NULL, -- "the posterior probability that the site is under evolutionnary selective pressure"
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY p (p)
);
--
-- Table structure for table `pita`
--
DROP TABLE IF EXISTS `pita`;
CREATE TABLE `pita` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
ddG REAL NOT NULL, -- ddG = dGduplex (microRNA-target hybridization energy) - dGopen (energy required to make the target site accessible)
conservation REAL NOT NULL, -- site conservation (range 0˜1)
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY ddG (ddG),
KEY conservation (conservation)
);
--
-- Table structure for table `microcosm`
--
DROP TABLE IF EXISTS `microcosm`;
CREATE TABLE `microcosm` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
score REAL NOT NULL, -- miRanda score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY score (score)
);
--
-- Table structure for table `pictar`
--
DROP TABLE IF EXISTS `pictar`;
CREATE TABLE `pictar` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
score REAL NOT NULL, -- score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY score (score)
);
--
-- Table structure for table `mirdb`
--
DROP TABLE IF EXISTS `mirdb`;
CREATE TABLE `mirdb` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
score REAL NOT NULL, -- score
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY score (score)
);
--
-- Table structure for table `mir2disease`
--
DROP TABLE IF EXISTS `mir2disease`;
CREATE TABLE `mir2disease` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
disease VARCHAR(100) NOT NULL, -- disease
mirna_regulation VARCHAR(20) NOT NULL, -- how miRNA is regulated in the disease (up-regulated, down-regulated or normal)
experiment VARCHAR(40) NOT NULL, -- supporting experiment
year INTEGER UNSIGNED NOT NULL, -- year of the paper
title TEXT NOT NULL, -- title of the paper
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY disease (disease)
);
--
-- Table structure for table `pharmaco_mir`
--
DROP TABLE IF EXISTS `pharmaco_mir`;
CREATE TABLE `pharmaco_mir` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
target_uid INTEGER UNSIGNED NOT NULL, -- target gene unique ID
drug VARCHAR(40) NOT NULL, -- disease
pubmed_id VARCHAR(10) NOT NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
FOREIGN KEY (target_uid)
REFERENCES target(target_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY drug (drug)
);
--
-- Table structure for table `phenomir`
--
DROP TABLE IF EXISTS `phenomir`;
CREATE TABLE `phenomir` (
mature_mirna_uid INTEGER UNSIGNED NOT NULL, -- mature miRNA unique ID
pre_mirna_acc VARCHAR(20) default NULL, -- precursor miRNA accession
pre_mirna_id VARCHAR(20) default NULL, -- precursor miRNA ID
disease VARCHAR(60) NOT NULL, -- disease
disease_class VARCHAR(20) NOT NULL, -- disease class
mirna_expression VARCHAR(30) NOT NULL, -- how miRNA is expressed in the disease
study VARCHAR(40) NOT NULL, -- type of study (in cells, patients, etc)
experiment VARCHAR(40) NOT NULL, -- supporting experiment
pubmed_id VARCHAR(10) NOT NULL, -- PubMed ID
FOREIGN KEY (mature_mirna_uid)
REFERENCES mirna(mature_mirna_uid)
ON UPDATE CASCADE ON DELETE RESTRICT,
KEY disease (disease),
KEY disease_class (disease_class)
);
--
-- Table structure for table `metadata`
--
DROP TABLE IF EXISTS `metadata`;
CREATE TABLE metadata (
name VARCHAR(80) PRIMARY KEY,
value VARCHAR(255)
);
--
-- Table structure for table `map_metadata`
--
DROP TABLE IF EXISTS `map_metadata`;
CREATE TABLE map_metadata (
map_name VARCHAR(80) PRIMARY KEY,
source_name VARCHAR(80) NOT NULL,
source_version VARCHAR(20),
source_date VARCHAR(20),
source_url VARCHAR(255) NOT NULL
);
--
-- Table structure for table `map_counts`
--
DROP TABLE IF EXISTS `map_counts`;
CREATE TABLE map_counts (
map_name VARCHAR(80) PRIMARY KEY,
human_count INTEGER UNSIGNED NOT NULL,
mouse_count INTEGER UNSIGNED NOT NULL,
total_count INTEGER UNSIGNED NOT NULL
);
== testthat results ===========================================================
OK: 22 SKIPPED: 0 FAILED: 0
>
> proc.time()
user system elapsed
4.84 0.37 7.12
|
