pathwayPCA

This package is for version 3.9 of Bioconductor; for the stable, up-to-date release version, see pathwayPCA.

Integrative Pathway Analysis with Modern PCA Methodology and Gene Selection


Bioconductor version: 3.9

Apply the Supervised PCA and Adaptive, Elastic-Net, Sparse PCA methods to extract principal components from each pathway. Use these pathway- specific principal components as the design matrix relating the response to each pathway. Return the model fit statistic p-values, and adjust these values for False Discovery Rate. Return a data frame of the pathways sorted by their adjusted p-values. This package has corresponding vignettes hosted in the ''User Guides'' page of , and the website for the development information is hosted at .

Author: Gabriel Odom [aut, cre], James Ban [aut], Lizhong Liu [aut], Lily Wang [aut], Steven Chen [aut]

Maintainer: Gabriel Odom <gabriel.odom at med.miami.edu>

Citation (from within R, enter citation("pathwayPCA")):

Installation

To install this package, start R (version "3.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("pathwayPCA")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("pathwayPCA")
Create Data Objects HTML R Script
Importing Data HTML R Script
Introduction HTML R Script
Quickstart Guide HTML R Script
Test Pathway Significance HTML R Script
Visualizing the Results HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews CellBiology, Classification, CopyNumberVariation, DNAMethylation, DimensionReduction, Epigenetics, FeatureExtraction, FunctionalGenomics, GeneExpression, GenePrediction, GeneSetEnrichment, GeneSignaling, GeneTarget, Genetics, GenomeWideAssociation, GenomicVariation, Lipidomics, Metabolomics, MultipleComparison, Pathways, PrincipalComponent, Proteomics, Regression, SNP, Software, Survival, SystemsBiology, Transcription, Transcriptomics
Version 1.0.0
In Bioconductor since BioC 3.9 (R-3.6) (5 years)
License GPL-3
Depends R (>= 3.6)
Imports lars, methods, parallel, stats, survival, utils
System Requirements
URL https://gabrielodom.github.io/pathwayPCA/; https://github.com/gabrielodom/pathwayPCA
Bug Reports https://github.com/gabrielodom/pathwayPCA/issues
See More
Suggests airway, circlize, grDevices, knitr, RCurl, reshape2, rmarkdown, SummarizedExperiment, survminer, testthat, tidyverse
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package pathwayPCA_1.0.0.tar.gz
Windows Binary pathwayPCA_1.0.0.zip
Mac OS X 10.11 (El Capitan) pathwayPCA_1.0.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/pathwayPCA
Source Repository (Developer Access) git clone [email protected]:packages/pathwayPCA
Bioc Package Browser https://code.bioconductor.org/browse/pathwayPCA/
Package Short Url https://bioconductor.org/packages/pathwayPCA/
Package Downloads Report Download Stats
Old Source Packages for BioC 3.9 Source Archive