oncomix

This package is for version 3.14 of Bioconductor; for the stable, up-to-date release version, see oncomix.

Identifying Genes Overexpressed in Subsets of Tumors from Tumor-Normal mRNA Expression Data


Bioconductor version: 3.14

This package helps identify mRNAs that are overexpressed in subsets of tumors relative to normal tissue. Ideal inputs would be paired tumor-normal data from the same tissue from many patients (>15 pairs). This unsupervised approach relies on the observation that oncogenes are characteristically overexpressed in only a subset of tumors in the population, and may help identify oncogene candidates purely based on differences in mRNA expression between previously unknown subtypes.

Author: Daniel Pique, John Greally, Jessica Mar

Maintainer: Daniel Pique <daniel.pique at med.einstein.yu.edu>

Citation (from within R, enter citation("oncomix")):

Installation

To install this package, start R (version "4.1") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("oncomix")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("oncomix")
OncoMix Vignette HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews GeneExpression, Sequencing, Software
Version 1.16.0
In Bioconductor since BioC 3.6 (R-3.4) (6.5 years)
License GPL-3
Depends R (>= 3.4.0)
Imports ggplot2, ggrepel, RColorBrewer, mclust, stats, SummarizedExperiment
System Requirements
URL
See More
Suggests knitr, rmarkdown, testthat, RMySQL
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package oncomix_1.16.0.tar.gz
Windows Binary oncomix_1.16.0.zip
macOS 10.13 (High Sierra) oncomix_1.16.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/oncomix
Source Repository (Developer Access) git clone [email protected]:packages/oncomix
Bioc Package Browser https://code.bioconductor.org/browse/oncomix/
Package Short Url https://bioconductor.org/packages/oncomix/
Package Downloads Report Download Stats
Old Source Packages for BioC 3.14 Source Archive